Based on the typical oil sands of the 45° angle reservoir somewhere in Gansu province as the research object, an experimental model with the application of sodium hydroxide, sodium dodecyl benzene sulfonic acid and anionic polyacrylamide as the triple component ASP displacement agent was investigated using local oil sands as samples. The asp flooding on the secondary development of 45° angle oil sands reservoir effect after hotwater flooding was tested, and the changing laws of sweep area for displacement agent, flooding effect and production of different direction horizontal well were also studied. The results showed that, displacement agent flowed to transverse area and affected area increased significantly, making the oil sands recovery improved for 18.91%, and production of the horizontal well which parallel to inclination of the reservoir is higher.